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Oncology/Hematology

News, opinions and meeting coverage in oncology/hematology.

Close up photo of a cryoablation device.

Broader Use of Cryoablation for Early Breast Cancer?

High success rate, few adverse events in patients ineligible for initial trials

A photo of senator Amy Klobuchar speaking before President Joe Biden at the Earth Rider Brewery in Superior, Wisconsin.

Sen. Klobuchar Says She's Cancer-Free but Will Get Radiation for Small Calcification

Early-stage breast tumor first found and removed in 2021

Onco Break over a computer rendering of a cancer cell.

A First in Total Larynx Transplant; 'Sniffing' Out Lung Cancer; Gen X Cancer Toll

News, features, and commentary about cancer-related issues

A photo of squamous cell carcinoma on a man鈥檚 head.

Immunotherapy Combo Active in Advanced PD-L1-Negative HNSCC

Will promising response rates translate into a survival benefit?

Morning Break over illustration of a syringe, Covid virus, and DNA helix over a photo of green vegetation.

Spicy Chip Death Lawsuit; Gen X and Cancer; Extreme U.S. Temperatures

Health news and commentary gathered by 番茄社区app staff

A computer rendering of multiple myeloma cells.

Refractory Multiple Myeloma Responsive to Immunotherapy Plus Low-Dose Radiotherapy

A third of patients who had received multiple prior lines of therapy responded, small study shows

A computer rendering of CAR-T cells attacking B-cell lymphoma cells.

If CD19 CAR T-Cell Therapy Fails in Lymphoma, Try a CD22 Version

Durable response possible with treatment targeting a different antigen

Young girl's face with a red rash

Make the Diagnosis: Can You Explain Her Rash and Conjunctival Injection?

A 13-year-old Mexican girl was brought to the doctor by her father for a rash that developed on her face over the last 3 days.

A breast MRI image.

Novel Image Analysis IDs Women for MRI After Negative Mammography

AI tool quadruples cancer detection rates in early trial

A photo of Marty Kedian in Mayo Clinic鈥檚 Head and Neck Regenerative Medicine Laboratory in Scottsdale, Arizona.

Laryngeal Transplant Helped a Cancer Patient Speak Again in Pioneering Study

Transplants of this nature normally aren't an option for people with active cancer

A close up photo of melanoma.

Can Narrow Margins Suffice for Some Smaller Low-Risk Melanomas In Situ?

Strategy in a selected population could reduce morbidity and costs, researchers argue

Avoiding Neuropathy From Chemo; Predictive Value of Screening EKGs

Also in TTHealthWatch: OUD medication use, and heart disease trends in the U.K.

A photo of foods associated with the Mediterranean diet

Mediterranean Diet Tied to Lower Mortality Risk in Cancer Survivors

High levels of adherence associated with lower risk of all-cause and cardiovascular mortality

A close up photo of a semaglutide injection pen.

Popular Diabetes Drug Class Lowered Risk of 10 Obesity-Associated Cancers

For people with diabetes, cancer risks were reduced with GLP-1s versus insulin

Onco Break over a computer rendering of a cancer cell.

Celebrity Cancers Stoking Fear? Cisplatin Shortage Ends; Setback for Anti-TIGIT

News, features, and commentary about cancer-related issues

Belantamab Mafodotin: The Comeback Drug in Multiple Myeloma

Joseph Mikhael, MD, leads a discussion on the DREAMM-7 and DREAMM-8 trials

A computer rendering of an oligonucleotide aptamer attacking a cancer cell.

Can Oligonucleotide Infusions Really Fix Lyme, Cancer, and Other Diseases?

U.S. clinics market oligonucleotide therapy for a wide range of conditions, without much evidence

A computer rendering of a transparent body with cancer of the larynx highlighted.

More Data Link Obesity to Better Survival for Cancer Patients on Immunotherapy

Higher BMI also associated with improvements in functional outcomes in this setting

Experts Discuss Groundbreaking Advances in EGFR-Mutant Lung Cancer

Discussion highlights insights from the LAURA trial and others on emerging treatments

A close up photo of a man smoking an ecigarette.

Vapers May Be Less Likely to Undergo Lung Cancer Screening

"Former smokers who use e-cigarettes remain at increased risk of lung cancer," researchers say

A photo of a PET/CT scanner.

PSMA PET Beats MRI in Prostate Cancer Staging Study

Findings support PSMA PET in the preoperative workflow of intermediate- and high-risk tumors

Pivotal Studies in Double-Expressor DLBCL Yield Divergent Results

R-CHOP plus venetoclax falls short, while R-CHOP with HDAC inhibitor shows promise

A photo of a female physician examining a mammogram.

Screening Mammography Performance Improved, Workload Decreased With AI Assistance

How European data play out in U.S. mammography environment remains to be seen

A photo of a man standing on a balance board.

Neuromuscular Training Decreased Incidence of Chemo-Induced Peripheral Neuropathy

Incidence significantly reduced with two types of exercises versus usual care

Onco Break over a computer rendering of a cancer cell.

Unexplained CAR-T Death; Americans Spurn Sunscreen; Improving Diversity in Trials

News, features, and commentary about cancer-related issues

A photo of patients receiving chemotherapy in an infusion clinic.

Study Supports More Inclusive Clinical Trials With Broader Eligibility Criteria

No difference in adverse events, clinical benefit, OS for patients with or without waivers

A photo of a female teen wearing a head scarf being comforted by her mother.

Young Cervical Cancer, Leukemia Survivors at Greater Risk of Obstetric Complications

Population-based study suggests reassurance for most, high-risk strategies for some

CAR T-Cell Therapy in Functional High-Risk Multiple Myeloma

Joseph Mikhael, MD, leads a discussion on the subgroup analysis of CARTITUDE-4

A photo of a blue rubber gloved hand holding a test tube of blood labeled: PSA Test.

What's a Normal PSA Value for Transgender Women on Estrogen Therapy?

Study suggests threshold is too high to identify risk of prostate cancer in this population

A photo of a female technician preparing a chemotherapy treatment in a glove box.

Oncology Drug Shortages Persist, but Continue to Evolve

Supply-chain issues, unrealistically low prices for generics, hoarding, other factors to blame

A close up photo of the hands of an adolescent receiving infusion therapy.

Temsirolimus Plus Chemotherapy Fails in Rare Childhood Cancer

Adding the mTOR inhibitor didn't improve EFS in intermediate-risk rhabdomyosarcoma

A computer rendering of a liver under a red umbrella.

Real-World Analysis Identifies Meds Tied to Higher Risk of Liver Injury

Case reports may not be as reliable, researchers say

Combo of Approved Agents Active in High-Risk Large B-Cell Lymphoma

Our panel of experts discusses mosunetuzumab/polatuzumab vedotin for relapsed/refractory patients

A close up photo of an acupuncture needle between a woman鈥檚 fingers.

Acupuncture Reduced Hot Flashes Related to Endocrine Therapy for Breast Cancer

64% of women reported at least a 50% reduction in hot flash frequency and severity

FDA APPROVED crovalimab (Piasky) over a computer rendering of blood flowing inside a vessel.

Subcutaneous C5 Inhibitor Approved for PNH

Longer-acting crovalimab designed for more sustained effect and less treatment burden

Treating Advanced Breast Cancer After Progression on CDK4/6 Inhibitors

Results from postMONARCH offer one path

A photo of the HealthCare.gov website.

Court: Some Employers Can Exclude PrEP, Cancer Screenings From Insurance Coverage

Not all preventive care recommended by the USPSTF is threatened by the narrow ruling, however

FDA APPROVED adagrasib (Krazati) over a computer rendering of colorectal cancer.

Adagrasib Wins Accelerated Approval for KRAS-Mutant Colorectal Cancer

KRAS inhibitor plus cetuximab achieved 34% response rate, 85% disease control in early trial

ASTRO Guideline Addresses Specifics of HPV-Associated Oropharyngeal Cancer

Clinical landscape has shifted away from traditional risks for H&N cancer to HPV predominance

A computer rendering of a meningioma.

ALK Inhibitor Shows Promise in Rare, Progressive Tumor Types

Phase II study found brigatinib exceeded historical control by shrinking 10% of targeted tumors

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